Rapid Ward Assessment of Renal Function by Reflectance Photometric Determination of Plasma Creatinine

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Abstract
The Ames Seralyzer reflectance photometer and disposable reagent strips for the determination of plasma creatinine were evaluated in the laboratory and on a urology ward over a 3-month period. Principles of the instrument used are described, as are details of the evaluation procedures. Reproducibility of results under optimum conditions gave coefficients of variation < 7%. Under routine conditions of use, medical staff and laboratory analysts achieved high correlation with the routine laboratory method of analysis (r = 0.986, N = 108: r = 0.996, N = 102, respectively). Potential sources of inaccuracy were identified. Seralyzer determination of plasma creatinine can be rapidly, simply and reliably performed by medical staff on a urology ward, thereby facilitating assessment of renal function governed by clinical requirement rather than by laboratory convenience.