Hypercalcuric Rickets Associated with Renal Tubular Damage

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Abstract
Two cases of a rare form of renal tubular rickets are reported. The defect in the renal tubula only involves the reabsorption of phosphate, Ca, protein and amino-acids. Both patients showed clinical and radiological signs of rickets, hypercalcuria and tubular proteinuria. Radiological healing of the rickets was obtained with moderate doses of vitamin-D. Both patients showed much retardation in growth, remaining below the third percentile for height. The absence in both cases of a family history indicates that the renal tubular defect is acquired and not hereditary. Steatorrhoea and renal acidosis were excluded.