Specificity of the Treponema pallidum haemagglutination test. Analysis of results.

Abstract
The automated hemagglutination assay using T. pallidum antigen (AMHA-TP) and the Venereal Disease Research Laboratory (VDRL) test were used to examine 330,163 sera [human]. Reactive results were checked by the fluorescent treponemal antibody-absorption (FTA-ABS) test. When isolated reactivity or non-reactivity in the AMHA-TP test was investigated, an estimated margin of error of 0.07% probably wrong non-reactive and 0.008% presumably false non-reactive results was found. These figures were confirmed by randomized FTA-ABS tests on 504 sera with repeat AMHA-TP tests. The latter is still the most reliable and practicable method for mass screening for syphilis.

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