Kerosine Dermatitis

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Abstract
In four children, dermatitis developed following contact with kerosine-soaked clothing. Experimental reproduction of the disease was achieved in volunteer subjects by application of kerosine, supporting the view that kerosine dermatitis is of primary irritant type. Studies on the physical factors related to the skin irritability to kerosine demonstrated the following facts: (1) The skin of the Negroes appeared to be less irritable to kerosine than that of Caucasians; (2) the influence of aging is not clear, (3) no definite correlation was noted between the individual cutaneous response to kerosine and permeability of the horny layer measured by TCSA penetration time; (4) the blood circulation seems to be influencial in the skin irritability to kerosine, and the low irritability of the forehead can be explained by the richness of the dermal vasculature.

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