THE FATE OF INJECTED OXYTOCIN IN THE RABBIT
- 1 November 1959
- journal article
- research article
- Published by Bioscientifica in Journal of Endocrinology
- Vol. 19 (2) , 189-192
- https://doi.org/10.1677/joe.0.0190189
Abstract
SUMMARY: Oxytocin injected intravenously into anaesthetized rabbits disappears rapidly from the blood stream, and its disappearance is retarded in animals whose liver or kidneys have been excluded from the circulation. The rate of disappearance of injected vasopressin is similar to that of oxytocin in intact rabbits. Homogenates of rabbit liver and kidney inactivate oxytocin rapidly in vitro; the site of inactivation by the kidney is in the tubules and not in the glomeruli.Keywords
This publication has 2 references indexed in Scilit:
- THE METABOLISM OF EXOGENOUS AND ENDOGENOUS ANTIDIURETIC HORMONE IN THE KIDNEY AND LIVER IN VIVOBritish Journal of Pharmacology and Chemotherapy, 1957
- Inactivation of Oxytocin by Homogenates of Uteri and Other Tissues from Normal and Pregnant RatsExperimental Biology and Medicine, 1954