Discrimination among reduced folates and methotrexate as transport substrates by a phenylalanine substitution for serine within the predicted eighth transmembrane domain of the reduced folate carrier
- 18 October 1999
- journal article
- Published by Elsevier in Biochemical Pharmacology
- Vol. 58 (10) , 1615-1624
- https://doi.org/10.1016/s0006-2952(99)00257-9
Abstract
No abstract availableKeywords
This publication has 25 references indexed in Scilit:
- Multiple folate enzyme inhibition: mechanism of a novel pyrrolopyrimidine-based antifolate LY231514 (MTA)Advances in Enzyme Regulation, 1998
- Major Facilitator SuperfamilyMicrobiology and Molecular Biology Reviews, 1998
- Biochemistry and pharmacology of glycinamide ribonucleotide formyltransferase inhibitors: LY309887 and lometrexolInvestigational New Drugs, 1996
- Folate-based thymidylate synthase inhibitors as anticancer drugsAnnals of Oncology, 1995
- Isolation of Human cDNAs That Restore Methotrexate Sensitivity and Reduced Folate Carrier Activity in Methotrexate Transport-defective Chinese Hamster Ovary CellsJournal of Biological Chemistry, 1995
- Isolation of a Human cDNA That Complements a Mutant Hamster Cell Defective in Methotrexate UptakeJournal of Biological Chemistry, 1995
- Molecular Cloning of the Human Placental Folate TransporterBiochemical and Biophysical Research Communications, 1995
- Interaction between anions and the reduced folate/methotrexate transport system in L1210 cell plasma membrane vesicles: Directional symmetry and anion specificity for differential mobility of loaded and unloaded carrierThe Journal of Membrane Biology, 1984
- Structural requirements for anion substrates of the methotrexate transport system in L1210 cellsArchives of Biochemistry and Biophysics, 1983
- THE CHARACTERISTICS OF THE MEMBRANE TRANSPORT OF AMETHOPTERIN AND THE NATURALLY OCCURRING FOLATESAnnals of the New York Academy of Sciences, 1971