Spironolactone in combination with an oral contraceptive: an alternative treatment for hirsutism
- 1 September 1985
- journal article
- research article
- Published by Wiley in BJOG: An International Journal of Obstetrics and Gynaecology
- Vol. 92 (9) , 983-985
- https://doi.org/10.1111/j.1471-0528.1985.tb03081.x
Abstract
Summary. The clinical efficacy of a combination of spironolactone and an oral contraceptive pill (Conova 30) was assessed in 23 patients presenting with hirsutism of whom 20 completed 6 months of treatment. Of the 20 patients, 16 showed improvement on objective (Ferriman & Gallwey hair score) and subjective assessment. Serum levels of androgens (testosterone, androstenedione and 17‐hydroxy progesterone) were suppressed and sex hormone binding globulins were elevated. Nausea was the only significant side effect.Keywords
This publication has 5 references indexed in Scilit:
- Use of cyproterone acetate (CPA) in the treatment of acne, hirsutism and virilismPublished by Elsevier ,2003
- Treatment of hirsutism with spironolactoneJAMA, 1982
- FURTHER CLINICAL EXPERIENCEIN THE TREATMENT OF HIRSUTISM WITH CYPROTERONE ACETATEBJOG: An International Journal of Obstetrics and Gynaecology, 1979
- Study of steroid-protein binding by a novel “two-tier” column employing cibacron blue F3G-A-Sepharose 4B. I—Sex hormone binding globulinThe Journal of Steroid Biochemistry and Molecular Biology, 1977
- CLINICAL ASSESSMENT OF BODY HAIR GROWTH IN WOMENJournal of Clinical Endocrinology & Metabolism, 1961