Metabolism of 2-C14-pyruvate after adrenalectomy
- 1 December 1960
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Legacy Content
- Vol. 199 (6) , 1059-1063
- https://doi.org/10.1152/ajplegacy.1960.199.6.1059
Abstract
Normal and adrenalectomized rats were infused with 2 C14-pyruvate for 90 minutes. The carcasses and livers were then analyzed for glycogen, protein and fat. The radioactivity of whole tissue homogenates was also assayed. Normal rats formed a large amount of highly active liver glycogen; the adrenalectomized animals did not. The discrepancy was not accounted for by accumulation of C14 in any of the fractions or organs studied, although slightly increased amounts were found in the expired CO2 and in the blood plasma. It is suggested that increased carbohydrate utilization after adrenalectomy may be secondary to diminished glycogenesis and may occur over all available routes.This publication has 0 references indexed in Scilit: