Long-Term Vitamin C Treatment Increases Vascular Tetrahydrobiopterin Levels and Nitric Oxide Synthase Activity
- 10 January 2003
- journal article
- research article
- Published by Wolters Kluwer Health in Circulation Research
- Vol. 92 (1) , 88-95
- https://doi.org/10.1161/01.res.0000049166.33035.62
Abstract
In cultured endothelial cells, the antioxidant, l-ascorbic acid (vitamin C), increases nitric oxide synthase (NOS) enzyme activity via chemical stabilization of tetrahydrobiopterin. Our objective w...Keywords
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