The distribution of Nippostrongylus brasiliensis in prolonged infections in lactating and neonatally infected rats
- 1 June 1974
- journal article
- research article
- Published by Cambridge University Press (CUP) in Parasitology
- Vol. 68 (3) , 347-354
- https://doi.org/10.1017/s0031182000045881
Abstract
In lactating rats examined 3 weeks post infection, adult Nippostrongylus brasiliensis were found in the duodenum close to the pylorus. Worms migrated from the predilection site, shown by Brambell (1965) and Alphey (1970) to be approximately 25% down the intestine, during the second week of infection. A similar migration took place in neonatally infected rats.It was suggested that the migration was an active response to immunological damage. It could be prevented by early betamethasone treatment but only modified by treatment given late in infection.Keywords
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