Use of Organobismuth Derivatives for Arylation of Piperazines
- 1 May 1997
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 27 (10) , 1669-1675
- https://doi.org/10.1080/00397919708004076
Abstract
This communication presents the synthesis of N-phenylpiperazines (4), using the organobismuth compound (3) as arylating agent. Triarylbismuthine (3) was obtained by condensation of dry BiCl3 with the organolithium intermediate (2).Keywords
This publication has 8 references indexed in Scilit:
- Structure-Affinity Relationship Studies on 5-HT1A receptor Ligands. 2. Heterobicyclic Phenylpiperazines with N4-Aralkyl SubstituentsJournal of Medicinal Chemistry, 1994
- Synthesis of SubstitutedN-Arylpiperidines via Organobismuth DerivativesSynthesis, 1994
- Structure-affinity relationship studies on 5-HT1A receptor ligands. 1. Heterobicyclic phenylpiperazines with N4-alkyl substituentsJournal of Medicinal Chemistry, 1993
- Direct substitution of aromatic ethers by lithium amides. A new aromatic amination reactionThe Journal of Organic Chemistry, 1993
- Copper salts catalysis of N-phenylation of amines by trivalent organobismuth compoundsTetrahedron Letters, 1987
- Metallic copper catalysis of -arylation of amines by triarylbismuth diacylatesTetrahedron Letters, 1986
- Preparation, reactions, and physical properties of organobismuth compoundsChemical Reviews, 1982
- Pentachlorophenyl-arsenic, -antimony and -bismuth compoundsJournal of Organometallic Chemistry, 1979