Recognition of protein coding regions in DNA sequences
- 11 September 1982
- journal article
- research article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 10 (17) , 5303-5318
- https://doi.org/10.1093/nar/10.17.5303
Abstract
We give a test for protein coding regions which is based on simple and universal differences between protein-coding and noncoding DNA. The test is simple enough to use without a computer and is completely objective. The test has been thoroughly proven on 400,000 bases of sequence data: it misclassifies 5% of the regions tested and gives an answer of “No Opinion” one fifth of the time. We predict some new coding and noncoding regions in published sequences.Keywords
This publication has 31 references indexed in Scilit:
- Gene organization and primary structure of a ribosomal RNA operon from Escherichia coliPublished by Elsevier ,2004
- Lysis gene expression of RNA phage MS2 depends on a frameshift during translation of the overlapping coat protein geneNature, 1982
- Promoters in the E. coli replication originNature, 1981
- Multiple copies of iso-insertion sequences of IS1 in Shigella dysenteriae chromosomeNature, 1981
- Organization and Expression of Eucaryotic Split Genes Coding for ProteinsAnnual Review of Biochemistry, 1981
- Transfer-RNA, an early gene?The Science of Nature, 1981
- Periodic correlations in DNA sequences and evidence suggesting their evolutionary origin in a comma-less genetic codeJournal of Molecular Evolution, 1981
- The coding function of nucleotide sequences can be discerned by statistical analysisJournal of Theoretical Biology, 1981
- One gene's intron is another gene's exonNature, 1981
- Complete nucleotide sequence of the human δ-globin geneCell, 1980