EFFECT OF DEWORMING MEDICATION ON MICROBIAL-FLORA OF UPPER GASTROINTESTINAL-TRACT OF DOGS

  • 1 January 1976
    • journal article
    • research article
    • Vol. 26  (4) , 640-643
Abstract
Control cultures were taken at laporatomy of the stomach or stomach remnant, jejunum, and ileum of 26 adult dogs, 8 of which had gastric surgery 1 yr earlier. At 2 wk after the control cultures were taken, 17 of the 26 dogs, including all 8 which had prior surgery, were treated with anthelmintics, niclosamide, dichlorophene, methylbenzene and arecoline hydrobromide. At 2 wk after the anthelminthic treatment, or 4 wk after the control cultures were taken, the 26 dogs were recultured. Samples of microbial flora were obtained by direct needle aspiration employing anaerobic precautions. These samples were processed quantitatively and qualitatively using anaerobic and aerobic techniques. The specific sites cultured were the lower stomach or stomach remnant, proximal jejunum 15 cm distal to the ligament of Treitz, and distal ileum 45 cm proximal to the ileocecal valve. Bacteria isolated were predominately facultative aerobes. No fungi were isolated. Cultivation of spirochetes was not attempted. There was no significant qualitative or quantitative alteration of microbial flora caused by the anthelmintic treatment.

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