“Lego” Chemistry for the Straightforward Synthesis of Dendrimers
- 20 June 2003
- journal article
- research article
- Published by American Chemical Society (ACS) in The Journal of Organic Chemistry
- Vol. 68 (15) , 6043-6046
- https://doi.org/10.1021/jo0344438
Abstract
A new straightforward method of synthesis of dendrimers, using two branched monomers (CA2 and DB2), is described. Each generation is obtained in a single quantitative step, with only N2 or H2O as byproducts; generation 4 is obtained in only four steps. The end groups are alternatively phosphines and hydrazines; their versatile reactivity is illustrated by the reaction of generation 4 with a branched CD5 monomer, which increases the number of end groups in a single step from 48 to 250.Keywords
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