Burkholderia Is Highly Resistant to Human Beta-Defensin 3
Open Access
- 1 May 2003
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 47 (5) , 1739-1741
- https://doi.org/10.1128/aac.47.5.1739-1741.2003
Abstract
The bactericidal activity of the novel beta-defensin hBD-3 against 28 species and 55 strains of gram-positive cocci and gram-negative fermentative and nonfermentative rods was tested. All strains proved to be highly or intermediately susceptible to hBD-3 (minimal bactericidal concentration [MBC], ≤50 μg/ml), except for Burkholderia cepacia , for all 23 tested strains of which MBCs were >100 μg/ml.Keywords
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