Alternative splicing and genome complexity
Top Cited Papers
- 17 December 2001
- journal article
- Published by Springer Nature in Nature Genetics
- Vol. 30 (1) , 29-30
- https://doi.org/10.1038/ng803
Abstract
Alternative splicing of mRNA allows many gene products with different functions to be produced from a single coding sequence. It has recently been proposed as a mechanism by which higher-order diversity is generated. Here we show, using large-scale expressed sequence tag (EST) analysis, that among seven different eukaryotes the amount of alternative splicing is comparable, with no large differences between humans and other animals.Keywords
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