Trapping Prion Protein in the Endoplasmic Reticulum Impairs PrPC Maturation and Prevents PrPSc Accumulation
Open Access
- 1 January 2005
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 280 (1) , 685-694
- https://doi.org/10.1074/jbc.m407360200
Abstract
No abstract availableKeywords
This publication has 59 references indexed in Scilit:
- Mutant PrP Is Delayed in Its Exit from the Endoplasmic Reticulum, but Neither Wild-type nor Mutant PrP Undergoes Retrotranslocation Prior to Proteasomal DegradationJournal of Biological Chemistry, 2003
- Reversion of transformed phenotype in ovarian cancer cells by intracellular expression of anti folate receptor antibodiesGene Therapy, 2003
- Stimulation of PrPC Retrograde Transport toward the Endoplasmic Reticulum Increases Accumulation of PrPSc in Prion-infected CellsJournal of Biological Chemistry, 2002
- The Chaperone Protein BiP Binds to a Mutant Prion Protein and Mediates Its Degradation by the ProteasomeJournal of Biological Chemistry, 2000
- Identification of an epitope in the C terminus of normal prion protein whose expression is modulated by binding events in the N terminus 1 1Edited by F. CohenJournal of Molecular Biology, 2000
- THE TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHIESAnnual Review of Medicine, 1995
- Intracellular Immunization with Cytosolic Recombinant AntibodiesBio/Technology, 1994
- The Contribution of Contact and Non-contact Residues of Antibody in the Affinity of Binding to Antigen: The Interaction of Mutant D1.3 Antibodies with LysozymeJournal of Molecular Biology, 1993
- Further characterization of scrapie replication in PC12 cellsJournal of General Virology, 1990
- Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: Evidence for membrane cycling from Golgi to ERCell, 1989