The cytochrome chain of mitochondria exhibits variable H+/e− stoichiometry
Open Access
- 19 August 1991
- journal article
- Published by Wiley in FEBS Letters
- Vol. 288 (1-2) , 183-186
- https://doi.org/10.1016/0014-5793(91)81030-c
Abstract
A study is presented of the ←H+/e− stoichiometry for H+ pumping by the cytochrome chain in isolated rat liver mitochondria under level‐flow and steady‐state conditions. It is shown that the ←H+/e− stoichiometry for the cytochrome chain varies under the influence of the flow rate and transmembrane ΔμH+. The rate‐dependence is shown to be associated with cytochrome c oxidase, whose ←H+/e− ratio varies from 0 to 1, whilst the ←H+/c− ratio for the span covered by cytochrome c reductase is invariably 2.Keywords
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