Generalized Gangliosidosis: Impaired Cleavage of Galactose from a Mucopolysaccharide and a Glycoprotein
- 28 February 1969
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 163 (3870) , 946-947
- https://doi.org/10.1126/science.163.3870.946
Abstract
We have demonstrated a tenfold (or greater) reduction of the cleavage of galactose from a mucopolysaccharide and a glycoprotein in generalized gangliosidosis, a lysosomal beta-galactosidase deficiency disease. The bony abnormalities in this disease may be due to defective catabolism of mucopolysaccharides in connective tissue.Keywords
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