The Effective Dose of Dexamethasone for Antiemesis after Major Gynecological Surgery
- 1 November 1999
- journal article
- Published by Wolters Kluwer Health in Anesthesia & Analgesia
- Vol. 89 (5) , 1316-1318
- https://doi.org/10.1213/00000539-199911000-00046
Abstract
Although dexamethasone is effective for antiemesis, major side effects may accompany its perioperative use. To achieve the best antiemesis with the fewest side effects, dexamethasone 10 mg, 5 mg, 2.5 mg, and 1.25 mg were compared with placebo in surgical patients. We found 2.5 mg to be the minimum effective dose without discernible side effects.Keywords
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