Antimicrobial Agents for the Prevention of Urinary Tract Infection in Transurethral Surgery

Publisher Website
Google Scholar
Abstract
Chemoprophylaxis and disinfection of the operation site for the prevention of bacteriuria after a transurethral operation were assessed in controlled, prospective studies in men with sterile urine preoperatively. The majority of the control patients (65%) suffered postoperative bacteriuria compared to 38.6% after perioperative disinfection with chlorhexidine and .ltoreq. 10% after each of 2 other regimens (i.m. cephradine followed by oral nitrofurantoin and chlorhexidine disinfection followed by oral nitrofurantoin). The latter regimen is preferred since it avoids the use of agents with systemic action.