EXTRA-ARTICULAR MANIFESTATIONS ARE UNCOMMON IN SOUTHERN CHINESE WITH RHEUMATOID ARTHRITIS
- 1 March 1993
- journal article
- research article
- Published by Oxford University Press (OUP) in Rheumatology
- Vol. 32 (3) , 209-211
- https://doi.org/10.1093/rheumatology/32.3.209
Abstract
Rheumatoid arthritis is characterized by both articular and extra-articular manifestations. Few studies have addressed the prevalence of extra-articular manifestations in non-Caucasoid races. We have studied 153 Southern Chinese patients with RA and found that such features are uncommon when compared with previous reports in Caucasoids. The only extra-articular manifestations were rheumatoid nodules which were present in 4.6%, and episcleritis and cutaneous vasculitis in 0.7% each. A further 12.4% had mild sicca symptoms. These findings were in direct contrast with the severity of articular disease as 73% of patients had erosive disease which was graded as severe in 37%. The reason for the low prevalence of extra-articular manifestations is not known but may be due, in part, to the rarity of the HLA-DR4 subtype, HLA-Dw4 in the Southern Chinese population.Keywords
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