Sex Steroids in Guinea Pig Fetuses after Sexual Differentiation of the Gonads
- 1 November 1979
- journal article
- research article
- Published by Oxford University Press (OUP) in Biology of Reproduction
- Vol. 21 (4) , 905-908
- https://doi.org/10.1095/biolreprod21.4.905
Abstract
Concentrations of testosterone (T), dihydrotestosterone (DHT), estradiol-17β (E) and progesterone (P) were measured in plasma samples from individual guinea pig fetuses between Days 29-55 of gestation. Umbilical artery blood was collected in capillary tubes and steroid concentrations were measured by radioimmunoassay after chromatography. The T levels in the plasma of males were significantly higher on Day 35 than on Days 45 and 55 of gestation. Both T and DHT concentrations were significantly greater in males than in females on both Day 35 and Day 45. The E concentrations were below the sensitivity of the assay at all stages of development and no sex differences in P were found at any gestational age.This publication has 7 references indexed in Scilit:
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