Acyclic model peptides with ionophoretic activity
- 5 May 1986
- journal article
- research article
- Published by Wiley in FEBS Letters
- Vol. 200 (1) , 58-62
- https://doi.org/10.1016/0014-5793(86)80510-5
Abstract
Two linear synthetic peptides, N‐tBoc‐Pro‐Gly‐Ala‐NHCH3 and N‐tBoc‐Pro‐D‐Ala‐Ala‐NHCH3, have previously been shown by us to complex with Ca2+ and form 2:1 (peptide:calcium) complexes. Here we report their binding to Pr3+ and demonstrate, by 1H NMR, the peptide‐mediated transport of Pr3+ across dimyristoylphosphatidylcholine unilamellar vesicles via a 2:1 ion‐sandwich complex.Keywords
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