Prostaglandin biosynthesis and lipolysis in subcellular fractions from rabbit kidney medulla
- 15 March 1981
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 194 (3) , 957-961
- https://doi.org/10.1042/bj1940957
Abstract
Three separate prostaglandin-generating activities are associated with plasma membranes, mitochondria and microsomal fractions from rabbit kidney medulla. In the plasma membranes and mitochondria, but not in microsomal fractions, Ca2+ ions stimulate the activity of phospholipase A2, yielding selective release of arachidonic acid and linoleic acid and concomitant increase in prostaglandin E2 formation.This publication has 14 references indexed in Scilit:
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