Decursinol Angelate: A Cytotoxic and Protein Kinase C Activating Agent from the Root ofAngelica gigas
- 1 August 1997
- journal article
- letter
- Published by Georg Thieme Verlag KG in Planta Medica
- Vol. 63 (04) , 360-361
- https://doi.org/10.1055/s-2006-957701
Abstract
A cytotoxic compound was purified from the root of Angelica gigas Nakai by normal phase HPLC. As a result of the structure analysis by mass, IR, 1H-NMR, and 13C-NMR spectrometry, the compound was identified as decursinol angelate, a structural isomer of decursin, and characterized originally from Sesei grandivittatum. Decursinol angelate showed in vitro cytotoxicity and protein kinase C activating activities like decursin.Keywords
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