Effect of Age, Temperature and Inoculum Size on Non-Infective Vaccinia Virus Yields in Eggs.
- 1 October 1961
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 108 (1) , 219-224
- https://doi.org/10.3181/00379727-108-26897
Abstract
A relative increase in noninfective or incomplete vaccinia virus occurs during virus growth in the chorioallantoic membrane of 12-day-old eggs incubated at 26[degree]C and 30[degree]C. Vaccinia growth in membranes of eggs 8 and 15 days of age is reduced but no increase in non-infective vaccinia was found. Serial passage of high concentrations of vaccinia virus in 12-day-old eggs likewise failed to increase the proportion of noninfective virus.Keywords
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