The Total Synthesis of Antrimycin Dv; II:1Synthesis of Tetrahydropyridazinecarboxylic Acid and Its Incorporation into Peptides
- 1 January 1993
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 1993 (08) , 809-814
- https://doi.org/10.1055/s-1993-25947
Abstract
Appropriately protected di- and tripeptides containing (R, S)-tetra -hydropyridazine-3-carboxylic acids were synthesized via protected γ-formyl-α-hydrazinobutyric acids. The latter compounds are obtained from acetals of either ethyl γ-formylbutyrate or ethyl γ-formyl-α-oxobutyrate.Keywords
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