The determination of aromatic substitution patterns by nuclear magnetic resonance
- 1 February 1972
- journal article
- research article
- Published by Wiley in Magnetic Resonance in Chemistry
- Vol. 4 (1) , 1-25
- https://doi.org/10.1002/mrc.1270040102
Abstract
A method is described which permits the analysis of many substituted benzene compounds. The method is useful for mono‐through tetra‐ substituted aromatics. In ideal cases, the number and disposition of the substituents and the chemical shifts of the residual protons can be accurately determined. The method assumes approximate first order couplings and is useful for roughly 50% of all aromatics. Frequently observed anomalous spectra are also discussed.Keywords
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