Hyperbaric Oxygenation

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Abstract
ALTHOUGH logic dictates that many pathologic processes characterized by diffuse tissue hypoxia should be benefited by hyperbaric oxygen ventilation, little scientific evidence supports such a broad therapeutic concept. The reason for this is apparent from a review of the factors that affect tissue oxygenation in addition to the arterial oxygen tension: the oxygen carrying capacity of the blood; the presence of an adequate arterial, venous and capillary circulation; and the specific oxygen requirements of the tissue under consideration. Disease may alter one or all of these components simultaneously, resulting in hypoxic damage despite values for arterial oxygen tension (pO2 . . .

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