Polymorphism inPlasmodium vivaxMSA1 gene – the result of intragenic recombinations?
- 6 April 1993
- journal article
- research article
- Published by Cambridge University Press (CUP) in Parasitology
- Vol. 106 (4) , 335-345
- https://doi.org/10.1017/s003118200006707x
Abstract
SUMMARY: The diversity in a 925 bp portion of thePlasmodium vivaxMSA1 gene in isolates from the Philippines, China, the Solomon Islands and Papua New Guinea was investigated. A total of 74 base pair changes was found in the amplified fragment from 18 isolates. Most of these changes were single or double base pair substitutions. In several regions, these point changes were tightly linked with one set always present or always absent in the different isolates. Seven such blocks were identified. These blocks were present in different combinations in the different isolates indicating that extensive intragenic recombination has occurred.Keywords
This publication has 16 references indexed in Scilit:
- An RFLP map of the Plasmodium falciparum genome, recombination rates and favored linkage groups in a genetic crossMolecular and Biochemical Parasitology, 1992
- Plasmodium falciparum: Birds to humansParasitology Today, 1992
- Phylogeny of plasmodium falciparumParasitology Today, 1992
- Structure and expression of the gene for Pv200, a major blood-stage surface antigen of Plasmodium vivaxMolecular and Biochemical Parasitology, 1992
- Two types of sequence polymorphism in the circumsporozoite gene of Plasmodium falciparumMolecular and Biochemical Parasitology, 1992
- Two novel alleles within subfamilies of the merozoite surface antigen 2 (MSA-2) of Plasmodium falciparumMolecular and Biochemical Parasitology, 1992
- A clonal theory of parasitic protozoa: the population structures of Entamoeba, Giardia, Leishmania, Naegleria, Plasmodium, Trichomonas, and Trypanosoma and their medical and taxonomical consequences.Proceedings of the National Academy of Sciences, 1990
- Wild isolates of Plasmodium falciparum show extensive polymorphism in T cell epitopes of the circumsporozoite proteinMolecular and Biochemical Parasitology, 1989
- Allelic dimorphism in a surface antigen gene of the malaria parasite Plasmodium falciparumJournal of Molecular Biology, 1987
- Biosynthesis and processing of a Plasmodium falciparum schizont antigen recognized by immune serum and a monoclonal antibody.The Journal of Experimental Medicine, 1982