Brief Communication: Inhibition of Dimethylhydrazine-Induced Neoplasia of the Large Intestine by Disulfiram2

1 April 1975

journal article
research article
Published by Oxford University Press (OUP) in JNCI Journal of the National Cancer Institute

Vol. 54 (4) , 1005-1006
https://doi.org/10.1093/jnci/54.4.1005

Abstract

Disulfiram added to the diet of female CFt mice inhibited large-bowel neoplasia produced by repeated subcutaneous administrations of dimethylhydrazine (DMH). The mice on a control diet all showed multiple tumors of the large bowel after DMH treatments, whereas there was no evidence of neoplasia in mice given disulfiram.

Keywords

DIMETHYLHYDRAZINE
NEOPLASIA
TREATMENTS
CFT
ADMINISTRATIONS
DISULFIRAM2
REPEATED
BRIEF
SUBCUTANEOUS
BOWEL

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