Amplified microgravimetric gene sensor using Au nanoparticle modified oligonucleotides
- 17 May 2000
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- No. 11,p. 953-954
- https://doi.org/10.1039/b001737j
Abstract
A novel microgravimetric gene sensing system has been developed using an oligonucleotide anchored on the gold electrode of a quartz crystal microbalance and an Au nanoparticle modified oligonucleotide, both of which formed a sandwich-type ternary complex with the target DNA to give an amplified frequency response.Keywords
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