Isolation of Clostridium difficile from human jejunum: identification of a reservoir for disease?
Open Access
- 1 August 1986
- journal article
- research article
- Published by BMJ in Journal of Clinical Pathology
- Vol. 39 (8) , 861-862
- https://doi.org/10.1136/jcp.39.8.861
Abstract
The possibility that the small intestine may represent a reservoir for Clostridium difficile was studied, using segments of human jejunum collected at necropsy. Our results (three of 100 specimens positive for C difficile culture) support the hypothesis that C difficile can be found in human jejunum and that it adheres to the normal mucosa as a resident bacterium. These findings suggest that gastrointestinal disease caused by C difficile has an endogenous origin.This publication has 5 references indexed in Scilit:
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- Isolation of Clostridium difficile from the small bowel.BMJ, 1981
- Epidemiological aspects of Clostridium difficile-induced diarrhea and colitisThe American Journal of Clinical Nutrition, 1980
- Selective and differential medium for isolation of Clostridium difficileJournal of Clinical Microbiology, 1979