Multiple Homologies of Oligonucleotide Size Exist between Nucleic Acids of Picornaviruses

Abstract
A semi-quantitative analysis of hybrid formation between restriction enzyme-generated subgenomic fragments of cloned c[complementary]DNA prepared from RNA of foot-and-mouth disease virus (FMDV) strain O1K and radiolabeled RNA from bovine enterovirus, bovine rhinovirus or mengovirus indicated that the hybrids were of oligonucleotide size. They were located in those parts of the FMDV O1K genome that code for the 2 capsid proteins VP3 and VP1 and the precursor protein P52 as well at the 3'' end. No hybridization was observed with poliovirus type 1 RNA.

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