Progress and Trends in In Vivo Chelation of Uranium

Publisher Website
Google Scholar
Abstract
Accidental internal contamination of humans by uranium can induce radiological or chemical toxicity, their relative importance being dependent on the isotopic composition. The current approach for reducing the risk of biological effects is to administer chelating agents that will enhance the excretion of uranium. The results obtained with several phosphorus bearing compounds including phosphonic acids, diphosphonates, and phosphoalkylphosphates and with 3,4,3-LIHOPO, an effective agent for other actinides are presented here. The development of new approaches designed to optimise the decorporation of uranium carried out under the European Union Fourth Framework Program is described.

This publication has 0 references indexed in Scilit: