Does Anti‐Jra Cause Hemolytic Disease of the Newborn?
- 1 July 1981
- journal article
- research article
- Published by Wiley in Vox Sanguinis
- Vol. 41 (1) , 40-44
- https://doi.org/10.1111/j.1423-0410.1981.tb01010.x
Abstract
A Jr(a-) Japanese female developed anti-Jra during her 1st pregnancy. Both father and infant red cells were Jr(a+), and anti-Jra was eluted from the infant''s red cells. The antibody was determined to be IgG1. Hemolysis could not be definitively established from the clinical data. The pitfall of using the presence of jaundice as the sole evidence for hemolysis is emphasized. The present case, and other previously reported cases, do not unequivocally establish that anti-Jra causes significant hemolytic disease of the newborn (HDN). Amniocentesis probably should not be performed during the pregnancy of mothers sensitized to Jra antigen. Jra HDN is probably a mild disease, like ABO HDN.This publication has 15 references indexed in Scilit:
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