Beta-oxidation of Fatty Acids by Nocardia opaca

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Abstract
Summary: A study of the mechanism of breakdown of w-phenyl-substituted fatty acids by Nocardia opaca has been made. Acids with an odd number of carbon atoms in the side chain (phenylpropionic, phenylvaleric and phenylheptylic acids) were converted to benzoic acid, and cinnamic acid was an intermediate. o-Hydroxy-phenylacetic acid was identified as a common product when acids with an even number of carbon atoms (phenylacetic, phenylbutyric, phenylcaproic and phenylcaprylic) were used. This evidence supports β-oxidation as a mechanism of breakdown of short chain fatty acids by N. opaca.

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