Reticulol, an Inhibitor of Cyclic Nucleotide Phosphodiesterases

Abstract
About 1,200 microbial cultured filtrates have been screened for inhibition of cyclic nucleotide phosphodiesterases (EC 3.1.4.c] prepared from rabbit brains. One of the active agents was isolated and identified as reticulol (6,8-dihydroxy-7-methoxy-3-methylisocoumarin).