THE CONTROL OF IMMEDIATE SHOCK FOLLOWING HYPODERMIC MEDICATION

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Abstract
The thought of a possible constitutional reaction is always in the background for those who may be administering any large series of immunizing injections. This possibility occasionally becomes a reality, and when the reality does appear it is often a matter of grave consequence, leading even to death. One and a half years ago an unlooked for incident occurred in my office which started me off on a train of investigation designed to remove immediate shock as a complication of immunizing therapy. The history in brief is as follows: Case 1. —Mrs. J. M., aged 53, suffered from severe hay-fever and asthma due to the grasses and ragweeds. The condition started June 1 and lasted until about September 20. Four injections of a commercial timothy extract had already been given in two days by a short interval method. An injection of 0.048 mg. (16 units) was to be given at

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