CYCLOPHOSPHAMIDE, ADRIAMYCIN, METHOTREXATE, AND PROCARBAZINE (CAMP)-EFFECTIVE 4-DRUG COMBINATION CHEMOTHERAPY FOR METASTATIC NON-OAT CELL BRONCHOGENIC CARCINOMA

  • 1 January 1976
    • journal article
    • research article
    • Vol. 60  (9) , 1225-1230
Abstract
Twenty-three patients with metastatic non-oat cell bronchogenic carcinoma (MNOBC) were treated with cyclophosphamide, adriamycin, methotrexate and procarbazine (CAMP) after radiation therapy. Objective responses were seen in 11 of 23 patients (48%) with a projected median survival time of 12.5 mo. for responding patients and patients with stable disease. Lung, liver and cutaneous sites of involvement were highly responsive; bone involvement was less responsive. CAMP is an effective combination in the treatment of MNOBC and its use in patients with less advanced disease should be explored.