Acute Hemolytic Anemia in Primary Atypical Pneumonia Associated with High Titer of Cold Agglutinins

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Abstract
SEVERAL observers1 2 3 4 have reported cases of acute anemia occurring in patients with primary atypical pneumonia who have developed high titers of cold agglutinins (autohemagglutinins). Since all these patients, with 2 possible exceptions, had been given one of the sulfonamide drugs, an additional etiologic factor was present that these authors thought might have been the primary or a contributory cause of the hemolytic crisis.† In the case reported below, no sulfonamide drug or any other medicinal agent was used that could have been an etiologic factor responsible for the causation of the acute hemolytic anemia.Case ReportThe patient, a 34-year-old . . .

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