Canine Tracheal Blood Flow After Endotracheal Tube Cuff Inflation During Normotension and Hypotension

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Abstract
Model. Control TBFs through the individual rings in contact with the endotracheal tube cuff ranged between 26.6 ± 2.7 and 44.5 ± 5.0 with a mean of 35.0 ± 2.5 mL·min−1·100g−1 during normotension, and 15.0 ± 4.9 and 22.5 ± 5.0 with a mean of 18.9 ± 0.9 mL·min−1·100 g−1 during hypotension. TBF was reduced significantly at all elevated MCPs in both groups. TBF also was measured during normotension and hypotension after cuff inflation to 15 mm Hg MCP at 1-h intervals for 3 h. TBF was reduced significantly from control to 14.9 ± 1.5 mL·min−1·100 g−1 after 1 h during normotension, and continued to decline to 6.1 ± 0.9mL·min−1·100g−1 after 3 h. During hypotension, TBF decreased significantly from control to 6.1 ± 0.6 mL·min−1·100 g−1 at 1 h and remained unchanged at 3 h. These findings suggest that even at 20 mm Hg MCP, significant reductions in TBF may occur. For prolonged endotracheal intubation, especially during hypotension, significant reductions in TBF may occur at even lower MCP. Address correspondence and reprint requests to L. Bunegin, B.S., Department of Anesthesiology, The University of Texas Health Science Center, 7703 Floyd Curl Drive, San Antonio, Texas 78284-7838. Accepted for publication December 22, 1992. © 1993 International Anesthesia Research Society...

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