Varicella-Zoster Virus Transformation of Hamster Embryo Cells
Open Access
- 1 November 1980
- journal article
- Published by Microbiology Society in Journal of General Virology
- Vol. 51 (1) , 171-177
- https://doi.org/10.1099/0022-1317-51-1-171
Abstract
Varicella-zoster virus infection of primary hamster embryo cells resulted in oncogenic transformation. These transformed cells exhibited virus-specific antigens by immunofluorescence and developed surface Fc receptors. They induced aggressive fibrosarcomas when injected into inbred hamsters. The tumour-bearing hamsters develop antibodies to varicella-zoster antigens.Keywords
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