Morphology of lymphatic cells and of their derived tumours.

Open Access
Publisher Website
Google Scholar
Abstract
The morphological description of diseases of the lymphatic and reticulum cells, and the classification of neoplasms derived from these cells, are in a state of some confusion, which arises, in part at least, from the different approaches and terminology used by histopathologists and by cytologically orientated hematologists. The process of revision of the classification of [human] ML [non-Hodgkin''s malignant lymphoma] has brought into focus in recent years the fact that these disorders are neoplasms of the immune system and that the great majority of them are derived from lymphoid cells at various stages of functional and morphological modulation. In this review the strict adoption of any one classification is avoided, and within the limits of the data at present available the known entities are grouped according to the cell types of possible origin. The major topics are: lymphocytic malignant lymphoma; malignant lymphoma of germinal center cell origin; malignant lymphoma of immunoglobulin-secreting cells and lymphoplasmacytic discrasias; immunoblastic malignant lymphoma; lymphoblastic malignant lymphoma and acute lymphoblastic leukemia; and histiocytic disorders.