Quantitative Analysis of Constitutive and Inducible CYPs mRNA Expression in the HepG2 Cell Line Using Reverse Transcription-Competitive PCR

This publication has 17 references indexed in Scilit:

• Relationship between mRNA Levels Quantified by Reverse Transcription-Competitive PCR and Metabolic Activity of CYP3A4 and CYP2E1 in Human Liver
  Biochemical and Biophysical Research Communications, 1999
• Evaluation of Induction of CYP3A mRNA Using the HepG2 Cell Line and Reverse Transcription-PCR.
  Biological & Pharmaceutical Bulletin, 1999
• The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions.
  Journal of Clinical Investigation, 1998
• Quantification of Multiple Human Cytochrome P450 mRNA Molecules Using Competitive Reverse Transcriptase-PCR
  DNA and Cell Biology, 1998
• An Orphan Nuclear Receptor Activated by Pregnanes Defines a Novel Steroid Signaling Pathway
  Cell, 1998
• Preclinical evaluation of drug—drug interaction potential: present status of the application of primary human hepatocytes in the evaluation of cytochrome P450 induction
  Chemico-Biological Interactions, 1997
• [42] Use of human hepatocytes to study P450 gene induction
  Published by Elsevier ,1996
• 3-Methylcholanthrene-Mediated Induction of Cytochrome P4501A2 in Human Hepatoma HepG2 Cells as Quantified by the Reverse Transcription-Polymerase Chain Reaction
  Archives of Biochemistry and Biophysics, 1994
• Omeprazole, an inducer of human CYP1A1 and 1A2, is not a ligand for the Ah receptor
  Biochemical and Biophysical Research Communications, 1992
• Enzyme induction in the cytochrome P-450 system
  Pharmacology & Therapeutics, 1990