Preparation and Stability of 1,4-Oxathian-2-ones.
- 1 January 1984
- journal article
- research article
- Published by Danish Chemical Society in Acta Chemica Scandinavica
- Vol. 38b (2) , 101-108
- https://doi.org/10.3891/acta.chem.scand.38b-0101
Abstract
Several methods of preparation of various substituted 1,4-oxathian-2-ones [pecticide constituents] are described, including the acid-catalyzed ring closure of .delta.-hydroxy acids, prepared via .alpha.-halo ketones or .alpha.-halo acids, and the base-catalyzed ring closure of .beta.-haloethyl thioglycolate. 1,4-Oxathian-2-one is completely hydrolyzed in D2O to the hydroxy acid at a rate comparable to the hydrolysis of .delta.-valerolactone. The rate of the lactonization is estimated to be .apprx. 100 times smaller in oxathianone than in valerolactone.This publication has 0 references indexed in Scilit: