Heinz Body Phenomenon in Monkey Erythrocytes, a Quantitative Method

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Abstract
Heinz bodies have been demonstrated in the blood of monkeys following the oral admn. of phenylhydrazine hydrochloride. These bodies disappear from the circulating blood in normal monkeys more rapidly than they do from the blood of splenectomized animals. A quantitative method for determining the number of Heinz bodies is described. This method is based upon the observation that Heinz bodies are not hemolyzed in dist water. A comparative study is made of the number of Heinz bodies free in the plasma in blood smears stained with a combination of Wright''s and Giemsa''s stains with those remaining after treatment with dist. water. The latter technic is both simple and rapid.
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