Short‐ and long‐term treatment of Tourette's syndrome with clonidine

Publisher Website
Google Scholar
Abstract
Thirteen patients with Gilles de la Tourette''s syndrome were treated with clonidine (0.125-0.3 mg/d) for at least 60 wk. In a single-blind, placebo-controlled trial, 6 of the 13 patients were judged to be unequivocal responders to clonidine and 6 other patients had an equivocal response. There was significant improvement in motor and phonic tics, as well as in associated behavior problems, and there were no serious side effects. Tolerance to clonidine did not develop. Further placebo-controlled, randomized, double-blind studies of clonidine in Tourette''s syndrome are needed to establish the drug''s efficacy.

This publication has 1 reference indexed in Scilit: