Effect of Hypophysectomy and Growth Hormone on Glucose Uptake by Rat Epididymal Fat Tissue.

Abstract
The glucose uptake by excised fat tissue was significantly less in hypophysectomized rats (733 [plus or minus] 39 [mu]g./g. tissue/hr.) than in normal rats (1165 [plus or minus] 88 [mu]g./g. hr.). A single injection of bovine growth hormone (GH; 30 [mu]g) in hypophysectomized rats increased, 24 hours later, the glucose uptake to 970 [plus or minus] 60 [mu]g-/g- hr. Sera from hypophysectomized and GH-treated hypophysectomized rats increased glucose uptake by normal fat tissue to same extent as sera from normal rats.